Men's Health | Top 40 novel treatment findings

Pre-exposure prophylaxis reduces HIV transmission risk in men who have sex with men.

Increased awareness of serostatus, higher rates of serosorting, and reduced HIV transmission rates among MSM practicing seroadaptive behaviors, particularly in the context of PrEP and TasP.

Study published: 2020-11-29

Pre-exposure prophylaxis reduces HIV risk for men at high risk.

Increased awareness and knowledge of PrEP can lead to higher uptake and adherence, ultimately reducing HIV incidence among at-risk populations.

Study published: 2023-03-09

Mobility impacts ART retention in men

Men prioritize ART and make significant efforts to stay in care despite mobility challenges. Recommendations for improving ART retention include targeted counseling, peer support, and access to ART services anywhere in the country, which may enhance treatment adherence and health outcomes for mobile men.

Study published: 2022-11-11

Testosterone therapy reduces breast tissue density in trans masculine individuals.

TT was associated with increased lobular atrophy and decreased amounts of breast epithelium and stroma, suggesting a potential reduction in breast cancer risk for TMIs.

Study published: 2024-01-10

Testicular sperm extraction helps men with genetic infertility achieve fatherhood.

The study reported the successful birth of a healthy child through medically assisted reproduction, indicating that men with loss-of-function variants can achieve fatherhood despite infertility issues.

Study published: 2024-07-01

Antiretroviral therapy improves quality of life for HIV patients with depression.

The study found that addressing depression significantly improves the quality of life for HIV patients. Support from families and health workers can enhance coping mechanisms and community acceptance.

Study published: 2022-09-02

Diverse preferences for HIV PrEP care

Identifying diverse preferences for PrEP care can lead to improved uptake and persistence of PrEP among high-priority GBM populations, addressing barriers to access and enhancing program effectiveness.

Study published: 2024-05-31

Targeted HIV prevention strategies reduce infection rates in transwomen.

Positive outcomes include a reduction in HIV prevalence among transwomen through tailored prevention strategies, improved access to healthcare, and increased awareness of the specific needs of transwomen in HIV research and prevention efforts.

Study published: 2022-08-30

Statin medications lower cholesterol less effectively in women with SLCO1B1 *5 genotype.

Women with the *5 genotype had a higher incidence of clinically high total cholesterol despite statin treatment, indicating a need for genotype-guided statin selection to improve treatment effectiveness.

Study published: 2021-10-16

Targeted interventions improve ART retention

The primary outcome is six-month retention in ART care, with secondary outcomes including cost-effectiveness and rates of adverse events. The study aims to improve ART outcomes for men by providing tailored interventions.

Study published: 2022-12-26

The RITe intervention increases voluntary medical male circumcision uptake among men with STIs in Malawi.

The RITe intervention was found to be acceptable, feasible, and appropriate, leading to a 100% increase in VMMC uptake among the target population.

Study published: 2024-04-04

A WeChat mini-app increases HIV Pre-Exposure Prophylaxis uptake among gay and bisexual men in China.

The study aims to assess the feasibility and preliminary efficacy of the mini-app in increasing intentions to use PrEP and actual initiation rates among HIV-negative GBMSM in Guangzhou, China.

Study published: 2020-10-21

Combination interventions reduce HIV risk for young Black and Latinx sexual minority men and transgender women.

Identification of polysubstance use patterns can inform targeted interventions to reduce HIV risk among young Black and Latinx sexual minority men and transgender women.

Study published: 2022-11-11

High willingness for monkeypox vaccination

The study found that 81.5% of respondents were willing to accept vaccination, with higher acceptance among those eligible for vaccination (85.2%). Positive beliefs about the vaccine, such as perceived effectiveness and social norms favoring vaccination, were associated with higher willingness to accept the vaccine.

Study published: 2022-10-13

Tailored HIV and HCV prevention strategies improve outcomes for men who have sex with men and people who inject drugs.

Improved understanding of the distinct characteristics and needs of MSM-IDU and PWID-MSM, leading to more effective prevention strategies for HIV and HCV.

Study published: 2021-12-11

Pre-exposure prophylaxis reduces HIV risk in men who have sex with men.

The study found that MSM with indications for PrEP were about three times more likely to be using it compared to those without indications. However, there was a significant gap, with 68% of indicated MSM not currently using PrEP, indicating a need for improved access and education.

Study published: 2021-03-05

Mpox vaccine shows 84% effectiveness

High vaccination uptake in 2022 led to good coverage among those at higher risk, with an estimated vaccine effectiveness of 84% for one dose, and no hospitalizations among vaccinated cases in 2023.

Study published: 2024-02-28

Sexual violence increases PrEP use in MSM

The study found that MSM who experienced sexual violence were more likely to use PrEP than those who did not, indicating a potential positive outcome of increased PrEP use in this vulnerable population.

Study published: 2023-10-05

High PrEP awareness among Rwandan MSM

The study found that 73% of participants were aware of PrEP, and 96% expressed a strong willingness to use it, indicating a positive outlook for its implementation among Rwandan MSM.

Study published: 2023-11-01

Stable sexual behavior on long-term PrEP

The study found no increase in the number of casual sex partners or condomless anal sex acts over four years of PrEP use. STI incidence remained high but stable, with slight decreases in chlamydia and gonorrhea among daily PrEP users. Only two daily PrEP users were diagnosed with HIV during the first year on PrEP.

Study published: 2023-12-11

Medical circumcision reduces HIV risk

The study found that men who underwent MMC had a 50% reduced odds of being HIV positive compared to uncircumcised men. Additionally, traditionally circumcised men had a lower prevalence of HIV compared to uncircumcised men, although the reduction was not statistically significant.

Study published: 2023-11-22

Two-way text follow-up care reduces costs for male circumcision clients

The implementation of 2wT follow-up care resulted in an average savings of $3.56 per client compared to routine care, with even higher savings in rural settings. It improved client engagement and maintained high-quality care.

Study published: 2023-10-24

Access to LGBTQ affirming healthcare increases U=U awareness among gay and bisexual men aged 50 to 76.

Increased awareness, belief, and understanding of U=U; improved risk perception accuracy; higher likelihood of HIV testing among HIV negative men.

Study published: 2022-06-23

Co-produced partner notification intervention among men who have sex with men improves sexually transmitted infection treatment.

The expected outcome is a co-produced intervention and program theory that is suitable for testing in a future feasibility study, aimed at improving STI notification and treatment among MSM.

Study published: 2020-10-23

High willingness for monkeypox vaccination

The study found that a significant majority of participants (84.07% of unvaccinated and undiagnosed individuals) expressed willingness to be vaccinated against monkeypox. Additionally, many participants were open to adopting behavioral changes to reduce transmission risk, such as reducing attendance at sex parties and having fewer sexual partners.

Study published: 2022-12-05

PrEP reduces HIV risk in Black MSM

The study found that individuals with access to PrEP had a relative risk of HIV of 0.52, those who initiated but were not adherent had a risk of 0.48, and those who were adherent had a risk of 0.23 compared to those who did not initiate PrEP, indicating significant reductions in HIV risk with PrEP.

Study published: 2024-03-05

Unassisted community-based HIV self-testing increases testing rates among men who have sex with men and transgender women.

The study found a 9.8% HIV point prevalence among participants, with 60.2% of reactive individuals linked to further testing. The overall acceptability score for the HIVST kits was high, indicating they were well-received by users.

Study published: 2021-11-14

The Imvanex vaccine reduces mpox cases in high-risk gay men.

Positive outcomes include a reduction in mpox diagnoses among vaccinated individuals and increased immunity within the GBMSM population. The study found that vaccination was associated with a lower incidence of mpox among those with identified risk factors.

Study published: 2023-11-16

Alcohol use boosts PrEP initiation among young men with HIV risk.

High-risk alcohol use was associated with increased initiation of PrEP, with 35% of men in the high/very high-risk group starting PrEP compared to 18% in the no alcohol group. However, overall continuation of PrEP at 3 months was low, with only 30% remaining on the medication.

Study published: 2024-03-24

Self-exams detect anal cancer early

The study found that the sensitivity of ASE/ACE was 59.6%, and specificity was 80.2%. The concordance between self-examinations and clinician examinations was 0.73, indicating that self-exams can effectively identify abnormalities, especially as lesion size increases.

Study published: 2023-10-19

Pre-exposure prophylaxis reduces HIV risk for men who have sex with men during COVID-19.

The study found that while there was a significant decrease in sexual risk behaviors during the early pandemic, these behaviors increased again as restrictions were lifted, indicating a need for continued access to sexual health services.

Study published: 2020-11-12

COVID-19 disrupts HIV care in MSM

Modeling predicted an overall decrease in new HIV infections over one year (3-17%) despite disruptions, but an increase in deaths over one year (1-2%).

Study published: 2020-10-13

Case-based and population-based testing reduces gonorrhea outbreaks among men who have sex with men.

The implementation of combined case-based and population-based test-and-treat strategies significantly enhances the probability of eliminating emergent XDR strains and reduces outbreak size compared to current practices. However, outbreaks could persist for up to 2 years post-detection even with effective strategies.

Study published: 2021-05-03

Interventions reduced mpox transmission significantly

The combined interventions averted 46%-58% of mpox cases, with early vaccination having the largest impact, preventing 21%-39% of infections depending on city-specific factors.

Study published: 2024-06-21

The study improves HIV prevention by increasing PrEP use among men who have sex with men.

The model predicts that increasing PrEP coverage from 15% to 27% could avert 12.3% of HIV infections over 10 years, highlighting the interdependence of the interventions and the importance of budget allocation.

Study published: 2021-04-01

Cost-effective PrEP interventions for MSM

The interventions averted 0.2-4.2% of new infections and gained 0.0045%-0.24% quality-adjusted life years (QALYs) compared to the status quo, with the combination strategy being cost-effective at $86,927/QALY gained.

Study published: 2021-07-25

Different frequencies of plasmapheresis improve health outcomes in men.

Despite changes in haematological and biochemical parameters, exercise performance markers remained unchanged across all frequencies of plasmapheresis over the 3-month period.

Study published: 2023-06-05

Partner notification helps men who have sex with men reduce STIs.

The potential positive outcomes include increased identification and treatment of STIs among partners, reduced transmission rates, and improved health outcomes for MSM. Effective PN could lead to better engagement with health services and preventive measures such as HPV vaccination and HIV PrEP.

Study published: 2021-06-08

Chinese herbal medicine improves fertility

The study aims to provide high-quality evidence supporting the efficacy and safety of Chinese herbal medicine in enhancing fertility in subfertile men with varicocele, potentially leading to improved fertility rates and semen quality.

Study published: 2023-01-10

Surgical and conservative treatments improve jaundice symptoms in obstructive jaundice patients.

The study found that both men and women required similar total hospitalization days for treatment, and the incidence of cholithiasis was higher in females. The treatment effectively addressed the obstructive symptoms in patients.

Study published: 2022-12-30